Tuesday, October 18, 2011

Lab rats, mice & guinea pigs, Oh My!

Happy Hump Day!!!!!!  

That was the message from my radiation oncologist today...I am half-way through my 30 treatments!! Today was #16. Other than the daily drive, this is a walk in the park! I am starting to turn pink and by the end of it I will have the most effed up looking 'sunburn' you will ever see! Not that you'll see it though. :)

I have 99.9% decided to go on a clinical trial for a drug that has shown promise in reducing the recurrence rate of breast cancer, hence the title of today's blog. This is a decision I have really struggled with over the past couple of weeks. The good thing is that it is an established drug, so doctors already know the side-effects. The bad thing is that it is a double-blind study, which means neither I nor my doctor will know whether I will be receiving the drug or the placebo.

About the drug, it is called Metformin. It is used in patients with Type 2 diabetes to lower insulin levels. Doctors in Britain noticed that diabetes patients who had had breast cancer & had taken Metformin for diabetes had an almost 56% less chance of recurrence than other diabetics. Scientists are finding a link between the amount of insulin your body produces and the chance that you may develop breast cancer, apparently breast cancer cells 'feed' on insulin, so lowering the insulin may help lower the risk of recurrence.

It really took a lot of soul searching & prayer to come to this decision. At first I was afraid of how I would react if finding out I was on the placebo & my cancer came back. How would I take that on an emotional & mental level? How would my body react to the drug? It can't be any worse than chemo was, right?

In the end, it was my radiation oncologist that helped the most. Her advice was to "not feel guilty" what ever I chose to do. She was right. I was stressing about it too much. And knowing what kind of cancer I had, I will take any weapon I can put in my arsenal.

Please pray for me to get the drug - not the placebo!!! :)

In other news, Svensk Hyllningsfest came and went - whoosh! My mom's lung infection has reared it's ugly head again, but doesn't seem to be tucking it's tail and running from the antibiotics this time. Pray for her, too. Looks like we will be visiting with some pulmonary specialists soon. Mom's the one who taught me to fight, so I'll be right there with her the whole time, fighting some more.

So with that, everybody take a deep breath, have a moment of Zen, and keep us in your prayers. You are all in mine.

2 comments:

  1. The thing about a double blind study is that you have a 50/50 chance of receiving the drug. Depending on the outcome of the study, future patients may have a 100% chance of non-recurrance. Praying for you that you don't get placebo!

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  2. I know, 50/50 is better than 0 when it comes to my chances. Sometimes it is hard to put your own current situation aside in order to think about someone else's future struggles.

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